Timegated Raman Spectrometer
Thông số cơ bản
| Tiêu chuẩn: | Process Analytical Technology, GMP-oriented bioprocess monitoring |
| Ứng dụng: | Bioprocess monitoring, biomanufacturing, biopharmaceutical process analysis, critical process parameter monitoring, high-throughput screening |
| Công nghệ phân tích: | Timegated® Raman Technology, Raman Spectroscopy, fluorescence-suppressed Raman measurement |
| Nhà cung cấp: | Timegate Instruments Ltd. |
| Model: | PicoRaman M3 with Timegated® Raman add-ons |
- Timegated Raman Spectrometer by Timegate is designed for real-time bioprocess monitoring.
- The system uses Timegated® Raman Technology to provide Raman data with fluorescence suppression.
- The product family includes PicoRaman M3, ProbePro Mini, SampleCube, Microprobe and MicroPlate HTS System.
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Timegated Raman Spectrometer for Bioprocess Monitoring

Timegated Raman Spectrometer by Timegate is designed for real-time bioprocess monitoring.
The system uses Timegated® Raman Technology for Raman measurements with fluorescence suppression.
The product family is developed for complex processes in biomanufacturing.
It can be integrated into different phases of the bioprocess workflow.
Timegate offers PicoRaman M3 as the main spectrometer platform.
The system is used as a monitoring tool to optimize bioprocesses step by step.
It supports productive and profitable processing.
It also helps build adherence to Good Manufacturing Practice and quality standards.
The product family also includes probes and add-on products.
These are designed for different phases of biomanufacturing, from liquids to solids and from drug discovery to scale-up.
Products with Timegated® Raman Technology
Timegated® Raman products are flexible and easy-to-use instruments.
They are designed to be seamlessly integrated into bioprocesses.
The system provides access to real-time bioprocess monitoring and control.
It uses fast and high-accuracy measurements with Timegated® Technology.
PicoRaman M3 is the core spectrometer in the product family.
It is supported by add-on products for sampling, probing, microscopic analysis and high-throughput screening
The product family includes:
PicoRaman M3
ProbePro Mini
SampleCube
Microprobe
MicroPlate HTS System
Timegated® Raman Technology
Timegated® Raman Technology is used to improve Raman measurement in demanding samples.
The technology helps provide real fluorescence suppression.
This is important in bioprocess monitoring.
Fluorescence can interfere with Raman spectra and reduce data quality.
By suppressing fluorescence, the system can provide more useful Raman data.
This helps users follow process changes in real time.
The measurement technique is non-destructive.
It is also non-contact, label-free and easy to use.
Product Family – Timegated Raman Spectrometer
1. PicoRaman M3 – Timegated Raman Spectrometer
PicoRaman M3 is the main spectrometer platform from Timegate.
It provides real-time bioprocess monitoring and control.
The system uses fast, high-accuracy measurements with Timegated® Technology.
It is described as the first spectrometer in the biopharma market that provides real fluorescence suppression.
PicoRaman M3 supports safe monitoring.
The measurement technique is non-destructive, non-contact and label-free.
It is also designed to be easy to use.
This makes it suitable for bioprocess monitoring and control applications.

2. ProbePro Mini – Timegated Raman Spectrometer
ProbePro Mini is an add-on product family for PicoRaman M3.
It provides easy and continuous measurements of critical process parameters.
The measurement is performed through an optical interface.
This supports online and continuous monitoring in bioprocess applications.
ProbePro Mini is developed especially for liquid biopharmaceutical applications.
It is suitable for processes where critical process parameters need to be followed over time.

3. SampleCube – Timegated Raman Spectrometer
SampleCube is designed for sampling from a larger sample surface.
It helps provide more representative sampling through a larger surface area.
The sample cup holder can include eccentric rotation.
The measurement probe can also be moved in a scanning motion.
This design supports more representative sample measurement.
It is useful when the sample surface area needs to be covered more effectively.

4. Microprobe – Timegated Raman Spectrometer
Microprobe brings microscopic analysis to Timegated® Raman spectroscopy.
It is an accessory that can be installed with Olympus microscopes.
The accessory allows accurate identification of microscopic sample areas.
It also supports time-resolved analysis.
Microprobe is suitable for users who need Raman analysis at microscopic scale.
It extends the use of Timegated® Raman spectroscopy to small sample areas.

5. MicroPlate HTS System – Timegated Raman Spectrometer
MicroPlate HTS System is a well-plate reader.
It is developed to optimize High-Throughput Screening at the microscale.
The system uses a non-destructive and automated measurement technique.
It provides real-time and accurate data on the concentration of samples.
MicroPlate HTS System supports measurement of 96 samples in wells.
This makes it suitable for high-throughput screening workflows.

Applications
Timegated Raman Spectrometer is suitable for biomanufacturing and bioprocess applications.
It supports real-time monitoring and process understanding.
Typical applications include:
Bioprocess monitoring
Biomanufacturing
Biopharmaceutical process analysis
Critical process parameter monitoring
Liquid biopharmaceutical applications
Drug discovery
Scale-up
High-throughput screening
Microscopic Raman analysis
Real-time process monitoring
Online process monitoring
Technical Specifications
Product type:
Timegated Raman Spectrometer
Process Analytical Technology tool
Bioprocess monitoring system
Technology:
Timegated® Raman Technology
Raman Spectroscopy
Fluorescence-suppressed Raman measurement
Time-resolved Raman analysis
System configuration:
PicoRaman M3 spectrometer
ProbePro Mini
SampleCube
Microprobe
MicroPlate HTS System
Main components:
PicoRaman M3 for real-time bioprocess monitoring and control
ProbePro Mini for continuous measurements of critical process parameters
SampleCube for larger sample surface sampling
Microprobe for microscopic Timegated® Raman analysis
MicroPlate HTS System for 96-well high-throughput screening
Measurement mode:
Real-time measurement
Online monitoring
Continuous measurement with optical interface
Non-destructive measurement
Non-contact measurement
Label-free measurement
Automated measurement with MicroPlate HTS System
Applications:
Bioprocess monitoring
Biomanufacturing
Biopharmaceutical process analysis
Critical process parameter monitoring
Drug discovery
Scale-up
High-throughput screening
Microscopic sample analysis
Compatibility:
Bioprocess integration
Liquid biopharmaceutical applications with ProbePro Mini
Olympus microscopes with Microprobe
96-well plate workflows with MicroPlate HTS System
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